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GLP-1 support for cravings that are hard to shift

Oral semaglutide for alcohol cravings. Prescribed by a licensed physician when it is appropriate for you, on its own or alongside naltrexone, and delivered discreetly to your door.

$34 $49 Save 30%

Private doctor evaluation fee.

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2-Minute Online Assessment No commitment 100% private

Choose Your Horizon oral GLP-1 semaglutide

Oral GLP-1 drops beside naltrexone tablets

Track your goals and habits in the Choose Your Horizon app

GLP-1 medications are not FDA-approved to treat alcohol use disorder. Use for alcohol-related outcomes is off-label. The oral semaglutide offered through Choose Your Horizon is compounded.

Our physiciansLicensed in all 50 states

Oral dropsNo injections, no needles

Shipped free& discreetly

100% Private& Confidential

LegitScriptVerified healthcare merchant

4.5 ★★★★★300+ Trustpilot reviews

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GLP-1 treatment, made simple.

From evaluation to delivery, treatment happens from home.

Step 1

Complete your assessment

Answer questions about your drinking, health history, medications and goals in our short online assessment.

Step 2

Case is reviewed by a doctor

A licensed physician evaluates your information and determines whether oral GLP-1 is appropriate, on its own or alongside naltrexone.

Step 3

Medication delivered discreetly

If prescribed, your drops are shipped directly to your door in discreet packaging.

Start Assessment

Understanding GLP-1

A different route to the same quiet.Less pull toward the next drink.

GLP-1 medications act on signaling pathways involved in appetite, reward and cravings. Emerging research shows that semaglutide may help reduce how much people drink.

Early research is promising, but this is still an emerging area of medicine. GLP-1 medications are not currently FDA-approved to treat alcohol use disorder.

Illustration of GLP-1 acting on the brain's reward pathways — Where it works: GLP-1 acts on the reward and craving circuits, so the urge that leads to a drink can lose some of its force.

Hands cradling a warm mug in morning light

Quieter cravings

For some people, GLP-1 treatment may reduce the urge or desire to drink, making alcohol feel less difficult to resist.

The glass dropper, with a single drop forming at the tip

No needles

Our oral formulation is taken sublingually as drops according to your prescriber’s instructions. No injections or pens.

Alone or combined

GLP-1 and naltrexone appear to act on separate pathways, so some people are prescribed both.

You don’t have to decide your entire journey today.

Your Choose Your Horizon physician will evaluate whether GLP-1 is appropriate for you and help you start with a treatment plan that fits your goals.

See if GLP-1 Is Right for Me

What the research is showing

GLP-1s are being studied for more than weight loss.

Researchers are studying whether GLP-1 medications may also influence alcohol cravings and consumption. Early findings are encouraging, but the evidence is still developing.

Randomized clinical trial

9 weeks

In a 48-person randomized clinical trial, low-dose once-weekly injectable semaglutide reduced alcohol craving and some measures of alcohol consumption versus placebo. The trial found significant reductions in drinks per drinking day and weekly craving, while not all drinking outcomes changed significantly.

Hendershot et al. · JAMA Psychiatry · 2025n=48 · injectable semaglutide Read the study →

Real-world evidence

83,825

In a retrospective cohort of 83,825 people with obesity, semaglutide use was associated with a 50–56% lower risk of alcohol use disorder incidence or recurrence over 12 months compared with other anti-obesity medications. This was observational evidence and does not establish causation.

Wang et al. · Nature Communications · 2024Retrospective cohort · observational Read the study →

Evidence is growing

5 studies

A 2026 meta-analysis of five observational cohort studies found GLP-1 receptor agonist use was associated with a 28% lower risk of an alcohol use disorder diagnosis. The authors concluded that larger randomized trials are still needed.

Nasrollahizadeh et al. · Systematic review & meta-analysis · 2026Diabetology & Metabolic Syndrome Read the review →

Promising science. Still emerging.

GLP-1 medications are not FDA-approved to treat alcohol use disorder. Alcohol-related use is off-label. The studies above evaluated GLP-1 therapies and formulations that may differ from the compounded oral semaglutide offered by Choose Your Horizon. Published findings should not be interpreted as outcomes of Choose Your Horizon treatment. Individual results vary.

Explore the research →

Randomized clinical trial. Hendershot CS et al., JAMA Psychiatry (2025). Phase 2, double-blind randomized trial; 48 adults with AUD; 9 weeks; once-weekly subcutaneous semaglutide. Significant effects on laboratory alcohol consumption, drinks per drinking day, weekly craving and change in heavy drinking over time; average drinks per calendar day and number of drinking days were not significantly affected. Source
Real-world semaglutide cohort. Wang W et al., Nature Communications (2024). Retrospective electronic-health-record study of 83,825 patients with obesity; semaglutide associated with a 50–56% lower risk of AUD incidence or recurrence over 12 months versus other anti-obesity medications, with a replication analysis in a larger type 2 diabetes population. Association does not prove causation. Source
2026 meta-analysis. Nasrollahizadeh A et al., Diabetology & Metabolic Syndrome (2026). Five observational cohort studies; GLP-1 receptor agonist use associated with a 28% lower risk of AUD diagnosis (HR 0.72, 95% CI 0.59–0.89). The evidence base was limited and heterogeneous, and the authors called for further large-scale trials. Source
2025 systematic review. Alcohol and Alcoholism (2025). Three randomized trials (48–151 participants): semaglutide reduced alcohol use in one trial, dulaglutide lowered intake among current drinkers in another, while exenatide did not significantly reduce heavy drinking days. Source

The physicians behind your care

Expert physicians. Actually involved in your care.

Our medical leaders don’t sit on the sidelines. They develop our programs, see patients and help oversee care across Choose Your Horizon.

Daniel Montville, MD

Practicing Psychiatrist · Chief Medical Officer

Mayo Clinic-trained

Psychiatry Addiction medicine

Mayo Clinic-trained psychiatrist specialising in addiction medicine and behavioral health.

Emill Levasseur, MD

Practicing Physician · Senior Medical Advisor

Cornell-trained
Internal & Obesity Medicine

Internal medicine Obesity medicine

Cornell-trained physician with over a decade of experience in internal medicine and behavioral science.

Jessica Sanchez, MD

Practicing Addiction Physician · Medical Advisor

University of Minnesota-trained

Addiction medicine Behavioral health

University of Minnesota-trained physician specialising in addiction medicine and patient-centred care.

You're not just another case.You're a person with a plan.

Physician reviewedEvery plan is reviewed and approved by a licensed doctor.

Evidence-based careWe use treatments with real clinical evidence behind them.

Ongoing oversightYour progress is monitored and your plan evolves.

Whole-person supportMedication, coaching and health tracking, together.

More than medication

GLP-1 can be one part, not the whole plan.

Medication can address an important part of drinking behavior. But changing your relationship with alcohol can involve much more than taking a dose. That’s why Choose Your Horizon lets your care evolve around you.

Start simple. Add support when you need it.

Your goals can change. Your treatment can change with them.

Start Assessment

01
GLP-1
Oral semaglutide for cravings that are hard to shift, prescribed when appropriate.
You’re here
02
Naltrexone
FDA-approved medication that reduces the reward alcohol delivers and the cravings that follow.
Explore naltrexone →
03
Coaching
One-on-one support to help you work on habits, triggers, accountability and the life around your drinking.
Explore coaching →
04
Health monitoring
Simple at-home testing helps you and your care team understand what is happening beyond drinking alone.
Explore health monitoring →

Why Choose Your Horizon

Getting a GLP-1 is one thing. Getting the right care for your drinking is another.

GLP-1 medications are increasingly available online. Choose Your Horizon is different because your care is designed specifically around your relationship with alcohol, with physicians who can evaluate different treatment options and support that can evolve with you.

Features that matter		Typical medication-only care
Medical evaluation	✓	Varies
Alcohol-focused care	✓	Varies
Oral GLP-1 optionwhen appropriate	✓	Varies
Naltrexone available	✓	Varies
Combination treatmentwhen appropriate	✓	Varies
1:1 coaching available	✓	Rare
Health monitoring	✓	Varies
Treatment can evolve with you	✓	Varies
Drink less or quit, you choose	✓	Varies
Online from home	✓	Often

Why people choose Choose Your Horizon

Instead of stopping at a prescription, we combine physician-led medical care, GLP-1 or naltrexone when appropriate, and coaching and health monitoring you can add over time. Your physician helps determine the right level of support based on your goals.

30,000+people supported

4.5 ★on Trustpilot · 300+ reviews

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From real members

Trusted by people like you.

★★★★★ 4.5 out of 5

Based on 300+ verified Trustpilot reviews.

Simple, transparent pricing

You see your exact price after your consultation and before you commit to anything.

Oral GLP-1

$34$49physician evaluation

Medication billed separately after clinician approval.

Includes

✓Medical evaluation by a licensed provider
✓Oral GLP-1 prescription when appropriate
✓Monthly medication delivery
✓Option to combine with naltrexone
✓Ongoing message-based support
✓Free shipping and discreet packaging

Start Assessment

Delivery

Shipping & delivery

Free Shipping

All medication orders ship free of charge. No hidden fees.

2-3 Business Days

Your medication ships quickly and arrives within 2-3 business days after approval.

Discreet Packaging

All orders arrive in plain, unmarked packaging with no indication of contents.

Quality Assured

Compounded and dispensed by licensed, verified U.S. pharmacies.

Questions

Frequently asked questions

What is oral GLP-1 and how does it help with alcohol?

GLP-1 medications affect signaling pathways involved in appetite, reward and cravings. Research is showing these effects may also help reduce alcohol cravings and consumption.

Choose Your Horizon offers an oral compounded semaglutide option that may be prescribed when a licensed physician determines it is appropriate. GLP-1 medications are not FDA-approved to treat alcohol use disorder, so this use is off-label.

Is GLP-1 FDA-approved for alcohol cravings?

No. GLP-1 medications are not currently FDA-approved to treat alcohol use disorder or alcohol cravings.

Research into their effects on alcohol consumption and cravings is emerging. When prescribed for alcohol-related outcomes, the use is considered off-label.

Is this the same as GLP-1 injections used for weight loss?

GLP-1 refers to a class of medications that includes drugs used to treat diabetes and obesity. Choose Your Horizon’s program uses an oral compounded semaglutide formulation rather than a weekly injection.

Your physician will determine whether this treatment is appropriate for you.

Can I combine GLP-1 with naltrexone?

Potentially. For appropriate patients, a Choose Your Horizon physician may recommend GLP-1 treatment alone or alongside naltrexone.

Your clinician will consider your health history, medications, drinking patterns and goals before determining which treatment approach is appropriate.

Do I have to quit drinking before starting GLP-1 treatment?

Not necessarily. Choose Your Horizon works with people whose goal is to drink less as well as people who want to quit completely.

Your physician will provide individualized guidance based on your health, drinking patterns and treatment plan.

How quickly does GLP-1 treatment work for alcohol cravings?

Individual experiences vary, and research into GLP-1 medications for alcohol-related outcomes is still developing. Some patients may notice changes over time as treatment progresses, but no specific result or timeline can be guaranteed.

Your clinician can monitor your response and adjust your treatment plan when appropriate.

What are the side effects of GLP-1 medications?

GLP-1 medications can cause side effects, particularly gastrointestinal symptoms such as nausea, vomiting, diarrhea, constipation and abdominal discomfort. Other side effects and more serious risks are possible.

Your clinician will review potential risks, contraindications and what to watch for before prescribing treatment.

Who should not take GLP-1?

GLP-1 treatment isn’t appropriate for everyone. Your clinician will review your medical history, current medications and relevant risk factors before determining whether treatment is appropriate.

Be sure to provide complete and accurate medical information during your evaluation.

How much does Choose Your Horizon’s GLP-1 program cost?

The physician evaluation is $34. If you’re medically approved and choose to begin treatment, the program is $399 per month, including medication, ongoing clinical support and delivery.

Is Choose Your Horizon private, and where is treatment available?

Choose Your Horizon provides private online care from home. Clinical information is handled through secure systems, and medication is delivered in discreet packaging.

Availability and consultation requirements may vary by state. Not currently available in the following US states:

Alabama
Arkansas
Delaware
Indiana
Kansas
Louisiana
Minnesota
Mississippi
Missouri
New Mexico
Rhode Island
Vermont
Washington, District of Columbia
West Virginia

A woman on a sunlit porch in the morning

Ready to take the first step?

Start your quick online assessment. A licensed physician will review your case and prescribe oral GLP-1 if it is clinically appropriate for you.

Start Assessment

100% discreetNo needles Free shipping

You’re in good hands.

Physician-led care, licensed in all 50 states
Prescribed only when clinically appropriate
Delivered free and discreetly to your door
Message-based support between consultations

Cancel any time

GLP-1 support for cravings that are hard to shift

GLP-1 treatment, made simple.

Complete your assessment

Case is reviewed by a doctor

Medication delivered discreetly

A different route to the same quiet.Less pull toward the next drink.

Quieter cravings

No needles

Alone or combined

GLP-1s are being studied for more than weight loss.

Expert physicians. Actually involved in your care.

Daniel Montville, MD

Emill Levasseur, MD

Jessica Sanchez, MD

GLP-1 can be one part, not the whole plan.

GLP-1

Naltrexone

Coaching

Health monitoring

Getting a GLP-1 is one thing. Getting the right care for your drinking is another.

Trusted by people like you.

Simple, transparent pricing

Shipping & delivery

Free Shipping

2-3 Business Days

Discreet Packaging

Quality Assured

Frequently asked questions

Ready to take the first step?